Table 2 Serum bile acids in male and female offspring from control and HFD-fed dams.

From: Maternal High-Fat Diet Programs Offspring Liver Steatosis in a Sexually Dimorphic Manner in Association with Changes in Gut Microbial Ecology in Mice

Bile Acids

F-CH (mean ± SE)

F-HH (mean ± SE)

M-CH (mean ± SE)

M-HH (mean ± SE)

Diet

Sex

Interaction

aMCA

316.76 ± 35

338.54 ± 69.42

315.83 ± 60.71

547.33 ± 162.72

0.16

0.29

0.28

bMCA

23.64 ± 3.66

19.72 ± 4.26

18.41 ± 4.99

33 ± 5.85

0.33

0.78

0.09

CA

288.23 ± 33.08

252.03 ± 43.88

241.74 ± 45.81

511.16 ± 191.47

0.21

0.37

0.15

CDCA

21.82 ± 5.64

32.86 ± 14.69

22.13 ± 5.95

23.56 ± 4.69

0.43

0.70

0.52

DCA

283.02 ± 33.06

394.28 ± 23.29

147.27 ± 50.53

160.46 ± 51.29

0.22

<0.01

0.29

HDCA

22.33 ± 2.4

44.86 ± 21.69

48.9 ± 9.55

18.27 ± 1.65

0.96

0.92

0.10

UDCA

40.03 ± 5.93

32.78 ± 6.28

38.59 ± 5.96

35.22 ± 6.77

0.45

0.94

0.78

TaMCA

2458.95 ± 217

2064.74 ± 393

1979.51 ± 207

6993.62 ± 2546

0.05

0.13

0.05

TbMCA

98.84 ± 9.35

71.71 ± 6.23

80.44 ± 21.93

440.37 ± 261.7

0.17

0.23

0.15

TCA

378.56 ± 51.7

289.7 ± 27.64

183.15 ± 44.62

1898.35 ± 1251

0.16

0.31

0.16

TCDCA

31.17 ± 2.53

19.37 ± 3.22

24.42 ± 8.07

76.41 ± 34.39

0.20

0.23

0.09

TDCA

146.11 ± 23

134.64 ± 11.3

35.31 ± 6.56

67.99 ± 25.35

0.54

<0.01

0.30

THDCA

36.12 ± 2.76

22.5 ± 2.38

17.04 ± 5.39

36.35 ± 11.16

0.51

0.39

0.02

TUDCA

130.64 ± 9.87

96.78 ± 10.76

63.14 ± 3.86

155.5 ± 53.85

0.22

0.62

0.03

Total

4260.04 ± 290

3803.28 ± 487

3175.43 ± 156

10977.46 ± 4307

0.07

0.21

0.07

Conjugated

3280.38 ± 247

2699.43 ± 352

2383.01 ± 227

9668.59 ± 4061

0.08

0.19

0.07

Unconjugated

979.66 ± 85.27

1103.85 ± 139.38

792.42 ± 143.63

1308.87 ± 304.12

0.08

0.96

0.31

Back to article page