Figure 2
From: Hornerin contains a Linked Series of Ribosome-Targeting Peptide Antibiotics
Ultrastructural analyses of rHRNR2591–2684-treated S. aureus. TEM analyses of 6.25 × 107/ml S. aureus ATCC 6538, in 10 mM NaP, pH 5.5, treated with 312.5 µg/ml rHRNR2591–2684 for 2 h. Note the condensation of electron-dense cytoplasmic material and formation of membrane blebs (a–c). Occasionally ballooning (c) and aggregated cells (d), connected via electron-dense contacts, were found upon rHRNR2591–2684-treatment. (e,f) Control. Images are representative of two independent experiments, sampling on average 10 images.
