Figure 2
From: ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart
Integrin linked kinase (ILK) signaling. This pathway illustrates cytoskeletal changes and effects through integrin contacts with the extracellular matrix. (A) Differential gene expression in DKO mice versus WT mice. Red = upregulated, green = downregulated. A = activation, C = causes, E = Expression, EC = Enzyme Catalysis, I = inhibition, PP = Protein-Protein binding, RE = Reaction. (B) Differential gene expression in DKO mice after ACE-I. Red = upregulated, green = downregulated. A = activation, C = causes, E = Expression, EC = Enzyme Catalysis, I = inhibition, PP = Protein-Protein binding, RE = Reaction.
