Figure 5
From: ACE-inhibition induces a cardioprotective transcriptional response in the metabolic syndrome heart
Acute phase response. (A) Differential gene expression in DKO mice versus WT mice. (B) Differential gene expression in DKO mice after ACE-I. The acute phase response is a rapid inflammatory response that can –amongst others- be triggered by tissue injury. It consists of an increase in inflammatory factors and a change in concentration of several plasma proteins (the acute phase proteins). Red = upregulated, green = downregulated. E = Expression, I = inhibition, PP = Protein-Protein binding.
