Figure 1

Ultra-flexible microelectrode array (UF-MEA) designs and impedance measurements. (A) In vivo UF-MEAs with 32 channels. (Aa) In vivo rectangular UF-MEA design with 24 electrodes of 50 µm in diameter and 8 electrodes in a rhomboidal arrangement of 10 µm in diameter (see inset). (Ab) In vivo hemispheric UF-MEA design fabricated to cover one full hemisphere of a mouse cortex with 32 electrodes of 50 µm in diameter. White spaces represent via holes for tissue oxygenation and better material adhesion. (B) In vitro UF-MEA design composed of 16 electrodes of 50 µm in diameter. (C,D) Bode diagrams of the impedance (Z) measurements showing (C) module and (D) phase of the electrode impedance.