Figure 5
From: Molecular pain markers correlate with pH-sensitive MRI signal in a pig model of disc degeneration
Immunofluorescence of pain-related marker upregulation. Microphotographs showing IVD tissue samples after immunostaining against COMT, CGRP, and BDKRB1, and counterstaining with DAPI; the samples were examined 2, 6, and 10 weeks after intradiscal puncture. Merged panels of the various stains are presented in the right column (NP = nucleus pulposus, CGRP = calcitonin gene-related peptide, BDKRB1 = bradykinin receptor B1, COMT = catechol-O-methyltransferase).
