Table 2 Univariable, multivariable, and IPTW logistic regression analyses of CR failure.

	n	No. of events	(%)	Univariable analysis			Multivariable analysis			IPTW-adjusted analysis
	n	No. of events	(%)	Unadjusted OR	95% CI	p-value	Adjusted OR	95% CI	p-value	Adjusted OR	95% CI	p-value
(A) Overall phase
Antiemetics
Four-drug	22	8	36.4	0.35	(0.14–0.91)	0.030	0.22	(0.07–0.65)	0.006	0.27	(0.10–0.73)	0.009
Three-drug	108	67	62.0	1.00			1.00			1.00
Age (10 years)	—	—	—	0.66	(0.47–0.93)	0.017	0.60	(0.41–0.88)	0.009
BMI (1 kg/m²)	—	—	—	0.90	(0.83–0.98)	0.019	0.86	(0.78–0.95)	0.002
History of alcohol habit
Yes	46	21	45.7	0.47	(0.22–0.97)	0.041	0.30	(0.13–0.70)	0.005
No	84	54	64.3	1.00			1.00
(B) Acute phase
Antiemetics
Four-drug	22	7	31.8	0.36	(0.14–0.95)	0.040	0.22	(0.07–0.68)	0.008	0.28	(0.10–0.76)	0.013
Three-drug	108	61	56.5	1.00			1.00			1.00
Age (10 years)	—		—	0.53	(0.37–0.76)	0.001	0.47	(0.32–0.71)	<0.001
BMI (1 kg/m²)	—		—	0.91	(0.83–0.99)	0.025	0.87	(0.79–0.96)	0.006
History of alcohol habit
Yes	46	21	45.7	0.66	(0.32–1.36)	0.262	0.44	(0.19–1.03)	0.060
No	84	47	56.0	1.00			1.00
(C) Delayed phase
Antiemetics
Four-drug	22	3	13.6	0.18	(0.05–0.63)	0.008	0.13	(0.03–0.49)	0.003	0.15	(0.04–0.57)	0.005
Three-drug	108	51	47.2	1.00			1.00			1.00
Age (10 years)	—		—	0.93	(0.68–1.29)	0.678	0.90	(0.64–1.27)	0.549
BMI (1 kg/m²)	—		—	0.91	(0.83–1.00)	0.040	0.88	(0.80–0.96)	0.007
History of alcohol habit
Yes	46	15	32.6	0.56	(0.26–1.18)	0.128	0.38	(0.17–0.89)	0.025
No	84	39	46.4	1.00			1.00

IPTW, inverse probability of treatment weighting, OR, odd ratio; CI, confidence interval; BMI, body mass index.
Univariable, multivariable, and IPTW-adjusted logistic regression analyses were used to evaluate an antiemetic efficacy associated with CR failure.

Quick links

Search