Figure 1

Schematic representation of sample inclusion in experiments and data analysis. Peptide microarrays was performed with 33 samples from 30 patients, comprising a combination of tumor-infiltrating B lymphocyte (TIB) supernatants and serum samples. Following analysis of the resulting data, matching serum and TIB supernatant samples from 3 patients were used for comparative analysis of CMV/EBV peptide recogniton patterns in the tumor versus the periphery. We studied the matching TIL as well as PBMC responses to the top five viral peptides based on peptide microarray data, which lead to selecting a matched set of samples from only a single patient.