Figure 3

Individualized IgG recognition pattern of viral targets across patients. We performed a more detailed analysis in matching serum and TIB supernatant samples from three patients. Each patient displayed a unique IgG recoginition pattern of CMV and EBV epitopes. PanTT32 showed the strongest recognition of CMV pp65 peptides by TIB-IgG, and exhibited a shared recognition of all the viral peptides tested (from CMV and EBV proteins). BRT1 and BRT2 showed a much more pronounced recognition of viral proteins by serum IgG, albeit the shared recognition pattern (serum and TIB-IgG) was weaker compared to PanTT32.