Table 2 Genetic characterization of ZIKV P6 (a-f) sub-isolates.

From: Purified Inactivated Zika Vaccine Candidates Afford Protection against Lethal Challenge in Mice

clone

Mutations identified in E

Additional mutations identified in genome

genome nt position

amino acid

genome nt position

amino acid

P6-a

G1965T

E-V330L

nd

nd

P6-b

T1405G

(silent)

T2781G

NS1-W98G

P6-c

G1965T

E-V330L

nd

nd

P6-d

G1965T

E-V330L

nd

nd

P6-e

none

None

T2781G

NS1-W98G

P6-f

G1965T

E-V330L

nd

nd

  1. The sequence initially determined for ZIKV strain PRVABC59 was used as a reference sequence (GenBank access: KU501215.1). nd indicates not determined.