Figure 1
From: PIWI proteins contribute to apoptosis during the UPR in human airway epithelial cells
Real time analysis of 16HBE14o- cell survival during ER stress. (A) The cell conductances (expressed as normalized cell index) were accessed every 15 minutes following 24-hour treatment with TM (2.5 µg/ml), ALLN (100 µM) or DMSO (CTRL). The conductances were normalized to the last value prior to experiment start. The results from 3 measurements (n = 3) are plotted. ER stress-induced changes in BIP (B), CHOP (C), and NOXA (D) mRNA levels are shown. The results from 2 independent experiments (n = 8) are plotted normalized to TBP mRNA levels and expressed as a fold-change over the no stress controls. Error bars represent standard deviations. Significant changes (p < 0.05) are marked with an asterisk.
