Table 2 Cytoplasmic-Pin1 Staining and Clinicopathologic Characteristics of Melanoma Patients.
From: Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis
Variables | Cyto-Pin 1 Staining | |||
|---|---|---|---|---|
Low, No. (%) | High, No. (%) | Total | Pa | |
Primary melanoma | ||||
Age, y | ||||
≤60 | 152 (85.9) | 25 (14.1) | 177 | 0.872 |
>60 | 147 (86.5) | 23 (13.5) | 170 | |
Sex | ||||
Male | 169 (86.7) | 26 (13.3) | 195 | 0.760 |
Female | 130 (85.5) | 22 (14.5) | 152 | |
Tumor thickness, mm | ||||
≤1.0 | 104 (87.4) | 15 (12.6) | 119 | 0.855 |
1.01–2.00 | 79 (84.9) | 14 (15.1) | 93 | |
2.01–4.00 | 51 (83.6) | 10 (16.4) | 61 | |
>4.00 | 65 (87.8) | 9 (12.2) | 74 | |
Ulceration | ||||
Absent | 243 (86.5) | 38 (13.5) | 281 | 0.730 |
Present | 56 (84.8) | 10 (15.2) | 66 | |
Subtype | ||||
Lentigomaligna | 69 (94.5) | 4 (5.5) | 73 | 0.231 |
Superficial spreading | 110 (84.0) | 21 (16.0) | 131 | |
Nodular | 43 (82.7) | 9 (17.3) | 52 | |
Acrolentigous melanoma | 9 (81.8) | 2 (18.2) | 11 | |
Unspecified | 68 (85.0) | 12 (15.0) | 80 | |
Siteb | ||||
Sun-protected | 212 (76.5) | 39 (71.3) | 251 | 0.137 |
Sun-exposed | 87 (23.5) | 9 (28.7) | 96 | |
Metastatic melanoma | ||||
Age, y | ||||
≤59 | 82 (82.0) | 18 (18.0) | 100 | 0.753 |
>59 | 73 (80.2) | 18 (19.8) | 91 | |
Sex | ||||
Male | 109 (81.3) | 25 (18.7) | 134 | 0.916 |
Female | 46 (80.7) | 11 (19.3) | 57 | |
AJCC stage | ||||
I | 168 (85.7) | 28 (14.3) | 196 | 0.408 |
II | 131 (86.8) | 20 (13.2) | 151 | |
III | 65 (83.3) | 13 (16.7) | 78 | |
IV | 90 (79.6) | 23 (20.4) | 113 | |
