Table 3 Nulcear-Pin1 Staining and or Characteristics of MelanomaPatients.
From: Cytoplasmic Pin1 expression is increased in human cutaneous melanoma and predicts poor prognosis
Variables | Nulcear-Pin 1 Staining | |||
|---|---|---|---|---|
Low, No. (%) | High, No. (%) | Total | Pa | |
Primary melanoma | ||||
Age, y | ||||
≤60 | 129 (72.9) | 48 (27.1) | 177 | 0.608 |
>60 | 128 (75.3) | 42 (24.7) | 170 | |
Sex | ||||
Male | 146 (74.9) | 49 (25.1) | 195 | 0.698 |
Female | 111 (73.0) | 41 (27.0) | 152 | |
Tumor thickness, mm | ||||
≤1.0 | 87 (73.1) | 32 (26.9) | 119 | 0.008 |
1.01–2.00 | 59 (63.4) | 34 (36.6) | 93 | |
2.01–4.00 | 47 (77.0) | 14(23.0) | 61 | |
>4.00 | 64 (86.5) | 10 (13.5) | 74 | |
Ulceration | ||||
Absent | 206 (73.3) | 75 (26.7) | 281 | 0.509 |
Present | 51 (77.3) | 15 (22.7) | 66 | |
Subtype | ||||
Lentigomaligna | 56 (76.7) | 17 (23.3) | 73 | 0.977 |
Superficial spreading | 95 (72.5) | 36 (27.5) | 131 | |
Nodular | 39 (75.0) | 13 (25.0) | 52 | |
Acrolentigous melanoma | 8 (72.7) | 3 (27.3) | 11 | |
Unspecified | 59 (73.8) | 21 (26.3) | 80 | |
Siteb | ||||
Sun-protected | 184 (73.4) | 67 (25.7) | 251 | 0.603 |
Sun-exposed | 73 (74.7) | 23 (25.3) | 96 | |
Metastatic melanoma | ||||
Age, y | ||||
≤59 | 85 (85.0) | 15 (15.0) | 100 | 0.383 |
>59 | 73 (80.2) | 18 (19.8) | 91 | |
Sex | ||||
Male | 112 (83.6) | 22 (16.4) | 134 | 0.630 |
Female | 46 (80.7) | 11 (19.3) | 57 | |
AJCC stage | ||||
I | 135 (68.9) | 61 (31.1) | 196 | 0.0001 |
II | 122 (80.8) | 29 (19.2) | 151 | |
III | 73 (93.6) | 5 (6.4) | 78 | |
IV | 85 (75.2) | 28 (24.8) | 113 | |
