Table 1 Disease features of C57BL/6 mouse groups immunized with amyloid-β with or without PT.
Group | Antigen | PT | bvPLA2 | Survival rate (%) | Inflammatory infiltration | CD3+ cells | Macrophages |
|---|---|---|---|---|---|---|---|
1 | — | — | — | 10/10 (100) | 0.1 ± 0.3 | 1.23 ± 0.8 | 0.46 ± 1.2 |
2 | Aβ1-42 | No | No | 10/10 (100) | 0.13 ± 0.3 | 0.25 ± 1.2 | 0.61 ± 1.4 |
3 | Aβ1-42 | Yes | No | 6/10 (60) | 18.9 ± 1.9 | 12.21 ± 1.6 | 15.3 ± 2.0 |
4 | Aβ1-42 | Yes | Yes | 10/10 (100) | 0.37 ± 0.1 | 1.25 ± 0.8 | 1.22 ± 0.6 |
5 | — | Yes | No | 9/10 (90) | 0.14 ± 0.6 | 1.7 ± 0.7 | 0.7 ± 0.4 |
