Table 1 Patient characteristics.
Patient | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
Age (yrs) | 72 | 66 | 69 | 68 | 68 |
PSA (ng/ml) | 79.5 | 35.7 | 28 | 19.7 | 26.6 |
Stage | |||||
pT | T3a | T3b | T3b | T3a | T3b |
pN | N0 | N1 | N1 | N1 | N1 |
cM | M0 | M0 | M0 | M0 | M0 |
Gleason score (Biopsy) | 4 + 5 | 4 + 4 | 4 + 4 | 4 + 5 | 5 + 4 |
Number of suspect mpMRI lesions | 1 | 2 | 1 | 3 | 2 |
Number of biopsies for genomic analysis | 6 | 9 | 9 | 12 | 9 |
Number of biopsies with highly significant CNAs | 4 | 4 | 4 | 3 | 7 |
Average number of highly significant CNAs in positive biopsies | 4.25 | 6.25 | 4.5 | 3.7 | 2.1 |
Number of genomic index lesions | 1 | 2 | 2 | 1 | 1 |
Number of highly significant CNAs in genomic index lesion(s) | 7 | 7 | 6 | 6 | 4 |
Intra-prostatic location of genomic index lesion(s) (PI-RADS [v1]) | Left midgland, posterior, lateral peripheral/transition zone (9p/10p) | Right midgland, posterior, midlobar peripheral zone (3p) | Right midgland, posterior, midlobar transition zone (3p) | Right midgland, posterior, midlobar transition zone (3p) | Left midgland, posterior, lateral transition zone (10p) |
Gleason score at genomic index lesion(s) | 4 + 5 | 4 + 4 | 4 + 4/4 + 3 | 4 + 4 | Histopathologically no tumor |
Imaging findings at genomic index lesion(s): | |||||
Overall PI-RADS Score [v1] | 5 | 5 | 5 | 5 | 5 |
T2 | 4 | 5 | 5 | 3 | 5 |
DWI | 5 | 5 | 5 | 5 | 5 |
DCE | + | + | + | + | + |
ADC mean | 509 | 788 | 485 | 844 | 844 |
68Ga-PSMA-11-PET SUVmax | 65.8 | 20.9 | 37.2 | NA | 34.7 |
