Table 2 Sensitivity of the WT, ∆cmsA, ∆cmsB, and ∆cmsAB strains to antifungal agents (µg/mL).

From: Identification of Two Mannosyltransferases Contributing to Biosynthesis of the Fungal-type Galactomannan α-Core-Mannan Structure in Aspergillus fumigatus

 

MCFG

CPFG

AMPH-B

5-FC

FLCZ

ITCZ

VRCZ

MCZ

WT

0.015

0.25

1–2

64

>64

0.5

0.25–0.5

1–2

∆cmsA

0.015

0.25

1

4–8

>64

0.25–0.5

0.25–0.5

0.5

∆cmsB

0.015

0.25

1

16

>64

0.25

0.25–0.5

0.5

∆cmsAB

0.015

0.25

1

4

>64

0.25–0.5

0.5

0.5–1

∆cmsA::cmsA

0.015

0.25

1–2

64

>64

1

0.5

2

∆cmsB::cmsB

0.015

0.25

1–2

64

>64

0.5

1

2

  1. NOTE. micafungin (MCFG), caspofungin (CPFG), amphotericin B (AMPH-B), flucytosine (5-FC), fluconazole (FLCZ), itraconazole (ITCZ), voriconazole (VRCZ), and miconazole (MCZ).
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