Figure 5
From: Developmental induction of human T-cell responses against Candida albicans and Aspergillus fumigatus
Age-dependent IL-4 production by fungi specific T cells. (A,B) CD4+CD45RA+ T cells from neonates, infants, children, and adults were stimulated with C. albicans (orange) or A. fumigatus (blue) (as in Fig. 4) for 3 (left panel) and 6 days (right panel) respectively, and analysed for the expression of intracellular un-glycosylated IL-4 isoform (upper panel) and mature IL-4 (lower panel). Cumulative results are shown and each dot represents a different donor. The error bars in figures denote ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, as determined by one-way Anova with Tukey post hoc test.
