Figure 5

HFD-induced macrophage infiltration correlated with p16INK4a/p21 expression. Scatter plots of the number of p16INK4a-positive (a–c) and p21-positive (d–f) cells versus the MOMA-2-positive (a,d) and the Oil Red O-positive (b,e) area in the ascending aorta or versus the T-chol level in the plasma (c,f). Dots correspond to data from individual mice, as indicated. The Pearson’s correlation coefficient (r) and p-value (p) are shown.