Figure 2
From: Obesity shows preserved plasma proteome in large independent clinical cohorts
(A) Distributions of Log2 of the protein ratio fold-changes with respect to pool samples and (B) number of proteins identified per sample for the three cohorts (i.e., C1, C2A, and C2B). Scatter plots for individual protein SD obtained for the C1 cohort versus the C2 cohorts, (C) C2A and (D) C2B, and between the two collection days in C2 (E). The least variable - on average between the measurements - (green color) and most variable (red to orange color) commonly quantified proteins between the cohorts are displayed. Gender differences in the (F) C1 and (G) C2A, and (H) C2B. Mean relative quantitative proteins values, measured as the Log2 of the protein ratio fold-changes with respect to pool samples. The gray square represents the area for values comprised within the estimated technical variance. Only proteins with a high mean fold change difference between genders are shown in color. The full list of significant gender-specific proteins, are presented in Table 2. For C2, data were averaged over seven European collection centers.
