Table 2 Correlations between the levels of autophagy-related proteins in the CSF and conventional CSF or clinical markers in patients with PD.

From: Cerebrospinal Fluid Levels of Autophagy-related Proteins Represent Potentially Novel Biomarkers of Early-Stage Parkinson’s Disease

 

LC3-B

Beclin-1

ATG5

LAMP-2

r

p-value

r

p-value

r

p-value

r

p-value

α-synuclein (CSF)

0.51

<0.01

−0.15

NS

0.17

NS

0.25

NS

Total tau (CSF)

0.51

<0.01

−0.27

NS

0.27

NS

0.20

NS

P-tau (CSF)

0.20

NS

0.30

NS

0.10

NS

−0.34

NS

Tau ratio (CSF)

−0.38

<0.05

0.16

NS

−0.07

NS

−0.29

NS

  1. PD: Parkinson’s disease; UPDRS: Unified Parkinson’s Disease Rating Scale; NMSS: Non-motor Symptom Scale; NS: not significant.
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