Figure 3
From: Phylogenetic and mutational analyses of human LEUTX, a homeobox gene implicated in embryogenesis
Genomic homogeneity of human LEUTX and other protein coding genes. Both scatter plots represent the average number of both, nonsynonymous (#N) and synonymous (#S), substitutions per individual (y-axis) in the phase 3 results of IGSR/1000G database40; (A) heterogeneous and homogenous mutations, and (B) homogenous mutations only. The dotted line is a regression between the CDS width (x-axis) and the average numbers of substitutions (y-axis). Label “L” is LEUTX. “4” is MUC4, which had the most non-synonymous mutations among #N > #S genes, and “D” is DPSS, which had the most synonymous mutations among #N < #S genes. The other labels G, H, K, M, O, P, S, X and Z are GLIS1, HHEX, KLF4, MYC, OTX2, POU5F1, SOX2, HLX and ZNF366, respectively.
