Table 1 Baseline Characteristics in Patients with AMI.

From: Sex Differences Associated With Circulating PCSK9 in Patients Presenting With Acute Myocardial Infarction

 

Male (n = 220)

Female (n = 61)

P value

Cardiovascular risk factors

      Age [years (\(\bar{{\rm{x}}}\) ± s)]

58.53 ± 12.83

68.64 ± 8.97

<0.001

      Hypertension [n (%)]

41 (18.64)

28 (45.90)

<0.001

      Diabetes mellitus [n (%)]

63 (28.64)

28 (45.90)

0.011

      Current smoking [n (%)]

162 (73.64)

4 (7.56)

<0.001

      BMI [Kg/m2 (\(\bar{{\rm{x}}}\) ± s)]

25.62 ± 3.50

24.87 ± 3.75

0.155

      Obesity [n (%)]

41 (18.64)

13 (21.31)

0.639

      Dyslipidemia [n (%)]

120 (54.55)

31 (50.82)

0.606

      Family history of CAD [n (%)]

61 (27.73)

13 (21.31)

0.314

Biomarkers

      TC [mmol/l, M (Q1, Q3)]

4.30 (3.70,5.10)

4.75 (3.88,5.35)

0.045

      TG [mmol/l, M (Q1, Q3)]

1.20 (0.80,1.70)

1.20 (0.80,1.90)

0.578

      HDL-C [mmol/l, M (Q1, Q3)]

1.29 (1.14,1.47)

1.39 (1.25,1.62)

0.007

      LDL-C [mmol/l, M (Q1, Q3)]

2.48 (1.94,3.13)

2.57 (2.08,3.23)

0.236

      Glucose [mmol/l, M (Q1, Q3)]

6.58 (5.06,8.71)

7.1 (5.70,10.30)

0.060

      HbA1c [%, M (Q1, Q3)]

6.00 (5.55,7.00)

6.50 (5.80,7.60)

0.015

      Hs-CRP [mg/L, M (Q1, Q3)]

1.96 (0.73,5.90)

2.17 (0.67,6.20)

0.973

      Uric acid [umol/L, M (Q1, Q3)]

332.5 (270.8, 399.5)

299 (238, 337)

0.001

      Hcy [umol/L, M (Q1, Q3)]

12.30 (10.35,16.25)

9.60 (7.70,12.83)

<0.001

      BNP [pg/ml, M (Q1, Q3)]

276 (117,754)

596 (184.5,1755)

0.002

Prior drug treatment

      Statin [n (%)]

42 (19.09)

11 (18.03)

0.852

      Aspirin [n (%)]

23 (10.45)

7 (11.48)

0.819

      Beta-blocker [n (%)]

13 (5.91)

4 (6.56)

0.851

      CCB [n (%)]

42 (19.09)

24 (39.34)

0.001

      ACEI/ARB [n (%)]

33 (15.00)

12 (19.67)

0.379

Coronary severity scores

      SYNTAX score

15 (9,21.5)

13.5 (8,19.5)

0.286

  1. BMI, body mass index; TC, total cholesterol; TG, total triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; HbA1c, glycosylated hemoglobin A; Hs-CRP, high-sensitive-C-reactive-protein; Hcy, homocysteic acid; BNP, B-type natriuretic peptide; CCB, calcium-channel blocker; ACEI, angiotensin converting enzyme inhibitor; ARB, angiotensin receptor blocker.