Figure 3
Construction of MXGSD-asthma PPI network. (A) MXGSD putative targets PPI network with 6265 nodes and 154 870 edges. (B) Asthma-related targets PPI network with 7405 nodes and 173 108 edges. (C) Interactive PPI network of MXGSD and asthma with 4885 nodes and 132 764 edges. (D) First central network evaluation with a core subset of 1194 nodes and 54 626 edges based on the median degree of 33. (E) Second central network evaluation with a core subset of 138 nodes and 3273 edges based on “‘BC’ > 471.658, ‘CC’ > 0.507, ‘DC’ > 214, ‘EC’ > 0.018, ‘LAC’ > 17.129, and ‘NC’ > 18.728”. Blue diamonds, pink diamonds, and yellow diamonds stand for other human proteins, component targets, and selected targets, respectively.
