Figure 2 | Scientific Reports

Figure 2

From: Fibronectin synthesis, but not α-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling

Figure 2

Periostin increases in gingival healing following gingivectomy. (A) Gingival tissues dissected from rats were assessed for POSTN gene expression. Isoform analysis using RT-PCR demonstrated the presence of 2 isoforms of POSTN. (B) Analysis of the wild-type isoform of POSTN using Taqman PCR showed periostin mRNA peaked at day 7 post wounding. Data represents mean fold gene expressions ± s.d. relative to control day 0 of 3 independent rats. Data was analyzed via one-way ANOVA (*p < 0.05). (C) Representative images of immunoreactivity for periostin of gingiva at 1, 3, 7, and 14 days post-wounding and unwounded gingiva (day 0). The inset of day 0 demonstrates periostin positive periodontal ligament (PDL), between the tooth (T) and the alveolar bone (AB). Regions of rectangular boxes are shown in (a–d) Scale bar, 50 μm.

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