Figure 3

Cell proliferation in gingival healing following gingivectomy in vivo. Gingivectomy was performed in rats. (A) Representative images of immunoreactivity for PCNA in gingiva at 1, 3, 7, and 14 days post-wounding. (B) Quantification of PCNA+ cells in the connective tissues of gingival sections from unwounded rat (day 0), and rats at 1, 3, 7, and 14 days post-wounding. Data represents mean PCNA+ cells ± s.d. of 3 rats. (C) Quantification of PCNA+ epithelial cells normalized to the length of the re-epithelized tissue of gingival sections from unwounded rat (day 0), and rats at 1, 3, 7, and 14 days post-wounding. Data represents number of PCNA+ cells normalized to the corresponding length of re-epithelized tissue (mm) ± s.d. of 3 rats. Data was analyzed via one-way ANOVA (*p < 0.05 and **p < 0.01 relative to day 0 and day 1, respectively).