Figure 8 | Scientific Reports

Figure 8

From: Flavonoids are identified from the extract of Scutellariae Radix to suppress inflammatory-induced angiogenic responses in cultured RAW 264.7 macrophages

Figure 8

Wogonin and wogonoside inhibit the activity of pNFκB-Luc. A luciferase reporter contains 5 repeat NFκB response elements, named pNFκB-Luc, was applied here. Transfected cells were treated with LPS (1 μg/mL) for 24 hours and then application with wogonin or wogonoside at different concentrations for another 2 days. The cell lysates were subjected to luciferase assay. Chemical structures of wogonin and wogonoside were shown. Data were expressed as percentage of control and in Mean ± SEM, where n = 3. *p < 0.05 as compared to the control.

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