Figure 3 | Scientific Reports

Figure 3

From: Genome-wide DNA Methylation and RNAseq Analyses Identify Aberrant Signalling Pathways in Focal Cortical Dysplasia (FCD) Type II

Figure 3

Canonical pathway analysis using MetaCore identified EGFR, PDGFR, and mTOR signalling as the top 3 canonical pathways modulated in FCD type II patients. Red thermometers show an object that is upregulated. The big arrows indicate the “pathway start”. GR: group relation; CS: complex subunit; B: Boxes on lines denote the type of regulation where P is phosphorylation, B is binding and Z is catalysis.

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