Table 2 Association (ka1, ka2) and Dissociation (kd1, kd2) Rate Constants in Bilayers Determined Using the Two-State Reaction Model.

From: Role of the Ebola membrane in the protection conferred by the three-mAb cocktail MIL77

 

ka1 ± SE (×103 1/Ms)

kd1 ± SE (1/s)

ka2 ± SE (×10−3 1/s)

kd2 ± SE (×10−3 1/s)

POPC

0.232 ± 0.019

0.156 ± 0.006

1.517 ± 0.058

0.132 ± 0.055

POPC:DPPC (1:1)

3.997 ± 0.84

1.559 ± 0.14

1.446 ± 0.12

5.399 ± 0.84

DPPC

3.210 ± 0.34

1.913 ± 0.16

1.509 ± 0.083

2.725 ± 0.48

POPC:Chol (2:1)

34000 ± 15000

11900 ± 5200

1.315 ± 0.072

3.109 ± 0.51

POPG

0.111 ± 0.019

0.194 ± 0.014

3.461 ± 0.083

0.014 ± 0.17