Figure 4

Bland-Altman plots of new and revised clearance estimates. Bland-Altman plot of clearance estimates obtained from the Schwartz approach compared to clearance estimates from a population pharmacokinetic two-compartment (left side) and three-compartment (right side) model. The bias (2.8 ml/min for the 2 compartment and 6.5 ml/min for the 3-compartment model) is represented by the thin solid line, the upper and lower limits of agreement by the dashed lines.