Figure 5 | Scientific Reports

Figure 5

From: Using a three-compartment model improves the estimation of iohexol clearance to assess glomerular filtration rate

Figure 5

Exemplary plot of the Schwartz approach applied to a simulated three-compartment concentration-time curve. Exemplary plot of simulated concentrations (dots) in a single, virtual subject, and the slow (dashed line) and slow + fast (solid line) components based on the Schwartz approach fitted to concentrations 10, 20, 30, 60, 120, 240 and 300 minutes post-dose. Underprediction is apparent for later concentrations, reflecting the overestimated clearance.

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