Table 4 Comparison of progesterone (P4) sensitivity and specificity relative to pregnanediol glucuronide (PDG) in the exploratory cohort (ovulation had not been otherwise identified). P4, progesterone; PDG, pregnanediol glucuronide.
PDG above luteal threshold concentration | PDG below luteal threshold conentration | ||
|---|---|---|---|
Ovulatory cycles (n = 20, from 13 women) | |||
P4 single sample cut-off confirmed ovulation | 25 | 2 | Sensitivity of single sample cut-off P4 relative to PDG: 0.89 |
P4 single sample cut-off did not confirm ovulation | 3 | 41 | Specificity of single sample cut-off P4 relative to PDG: 0.95 |
P4 two sample percent rise confirmed ovulation | 139 | 38 | Sensitivity of P4 two sample percent rise relative to PDG: 0.95 |
P4 two sample percent rise did not confirm ovulation | 8 | 375 | Specificity of P4 two sample percent rise relative to PDG: 0.91 |
Anovulatory cycles (n = 22, from 14 women) | |||
P4 single sample cut-off confirmed ovulation | 0 | 2 | Sensitivity of single sample cut-off P4 relative to PDG: 1.00 |
P4 single sample cut-off did not confirm ovulation | 0 | 86 | Specificity of single sample cut-off P4 relative to PDG: 0.98 |
P4 two sample percent rise confirmed ovulation | 26 | 47 | Sensitivity of P4 two sample percent rise relative to PDG: 0.87 |
P4 two sample percent rise did not confirm ovulation | 4 | 539 | Specificity of P4 two sample percent rise relative to PDG: 0.92 |