Figure 3
From: A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells
Recognition of fibroblasts at different time points after infection with different HCMV strains. (a) Expression levels of gB in HFF within 4 days after infection with the HCMV strains AD169, Towne and Toledo (MOI 1). Shown is one representative experiment. (b) Normalized levels of IFN-γ secreted by CD3/28 activated T cells, which were redirected by the gB-BiTE antibody construct and co-cultured with HFF at different time points after infection with the indicated HCMV strains (mean ± standard deviation; n = 3).
