Figure 2 | Scientific Reports

Figure 2

From: Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

Figure 2

GO (gene ontology) term enrichment analysis. (A) Longitudinal transitions of GO-terms of normal control from D2 to D8. The enriched GO-terms of D2 control versus D0 control (blue) was ranked by normalized enrichment score (NES), and then the NES of GO-terms of D8 control versus D0 control (red) were overlaid. (B) The effect of GO enrichment profile of D2 ethanol. NES ranking of D2 control versus day 0 control (blue) was overlaid by the NES of D2 ethanol binge versus day 0 (red), and D2 control versus D2 ethanol (green). (C) The effect of GO enrichment profile of D8 continuous ethanol. NES ranking of D8 control versus day 0 control (blue) was overlaid by the NES of D8 continuous ethanol versus D0 (red), and D8 control versus D8 ethanol (green). (D) The effect of GO enrichment profile of D8  ethanol withdrawal. NES ranking of D8 control versus D0 control (blue) was overlaid by the NES of D8 ethanol withdrawal versus D0 (red), and D8 control versus D8 ethanol withdrawal (green). The Y-axis shows NES and the X-axis is the ranked GO-terms. This shows how the control (red) profile was altered by various ethanol treated profiles (blue, green).

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