Figure 3 | Scientific Reports

Figure 3

From: Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

Figure 3

Clustering of differentially expressed genes (DEGs) and their comparison. The log2 fold changes of 20160 mm10 ensemble genes were clustered using 2-dimentsional Euclidean algorithm. Color bar represents the log2 fold change values. (A) Three differentially expressed genes (DEGs): D2 control versus D0 control (D2Con); D2 ethanol versus D0 control (D2BE); D2 ethanol versus D2 control (D2C_D2BE). (B) Five DEGs: D8 control versus D0 control (D8CN); D8 ethanol withdrawal versus D0 control (D8WE); D8 continuous ethanol versus D0 control (D8CE); D8 ethanol withdrawal versus D8 control (CN_WE); D8 continuous ethanol versus D8 control (CN_CE). The right part of each panel is expression heatmap with color intensity representing differential expression level, for example D8 ethanol withdrawal versus D8 control (CN_WE). (C) The overlaps of the up-regulated gene lists in three ethanol treatment conditions. (D) The overlaps of the down-regulated gene list in three ethanol treatment conditions. The DEGs were selected using FDR < 0.05 in edgeR analysis.

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