Figure 7 | Scientific Reports

Figure 7

From: Genome-Wide Transcriptome Landscape of Embryonic Brain-Derived Neural Stem Cells Exposed to Alcohol with Strain-Specific Cross-Examination in BL6 and CD1 Mice

Figure 7

Gene networks and canonical pathways associated with brain/neuronal morphology upon continuous ethanol exposure. (A) Overlapping gene networks contributing to different cellular/neuronal morphologies using both significant (FDR < 0.05) and fold changes (>1.5) cut off. The gene expression fold changes within the network are also shown under each gene. “Data were analyzed through the use of IPA (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis).” (B) The fold changes of genes, which are involved in neuronal morphology. Note all genes shown in figure are changed in a statistically significant manner. N = 3. Significant differences from untreated D8 controls are indicated with *P < 0.05, **P < 0.01, ***P < 0.001, or ****P < 0.0001.

Back to article page