Table 2 Centrality Analysis Gene Results.
From: Conserved Transcriptional Signatures in Human and Murine Diabetic Peripheral Neuropathy
Symbol | Description | Degree (p-value) | Closeness (p-value) | Betweenness (p-value) | Eigenvector (p-value) |
|---|---|---|---|---|---|
PIK3CA | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 406 (p = 1.8E−08) | 0.00081 (p = 6.4E−01) | 43246.5 (p = 0.0E + 00) | 0.16 (p = 2.9E−03) |
MAPK8 | mitogen-activated protein kinase 8 | 372 (p = 3.8E−07) | 0.00078 (p = 6.6E−01) | 30937.8 (p = 0.0E + 00) | 0.15 (p = 6.3E−03) |
CD44 | CD44 molecule (Indian blood group) | 349 (p = 1.3E−08) | 0.00075 (p = 6.6E−01) | 32129.4 (p = 0.0E + 00) | 0.13 (p = 7.3E−03) |
MAPK1 | mitogen-activated protein kinase 1 | 280 (p = 3.5E−03) | 0.00074 (p = 6.5E−01) | 19719.2 (p = 1.7E−03) | 0.13 (p = 3.9E−02) |
CREB1 | cAMP responsive element binding protein 1 | 283 (p = 1.2E−08) | 0.00073 (p = 6.4E−01) | 15524.7 (p = 0.0E + 00) | 0.12 (p = 3.0E−03) |
LEP | leptin | 301 (p = 8.7E−10) | 0.00072 (p = 6.6E−01) | 22639.7 (p = 0.0E + 00) | 0.12 (p = 5.6E−03) |
CCL2 | chemokine (C-C motif) ligand 2 | 276 (p = 3.3E−03) | 0.00071 (p = 6.9E−01) | 13595.3 (p = 4.5E−03) | 0.12 (p = 1.0E−01) |
JUN | jun proto-oncogene | 232 (p = 5.9E−03) | 0.00071 (p = 6.7E−01) | 11905.8 (p = 1.2E−02) | 0.12 (p = 4.3E−02) |
ESR1 | estrogen receptor 1 | 269 (p = 4.7E−09) | 0.00071 (p = 6.6E−01) | 17433.2 (p = 0.0E + 00) | 0.11 (p = 5.8E−03) |
FOS | FBJ murine osteosarcoma viral oncogene homolog | 229 (p = 3.1E−03) | 0.00070 (p = 6.4E−01) | 21885.2 (p = 2.5E−07) | 0.10 (p = 7.4E−02) |
CD36 | CD36 molecule (thrombospondin receptor) | 247 (p = 5.0E−07) | 0.00070 (p = 6.5E−01) | 11865.1 (p = 6.5E−13) | 0.11 (p = 7.2E−03) |
IL1B | interleukin 1, beta | 224 (p = 6.5E−03) | 0.00070 (p = 6.6E−01) | 12492.5 (p = 3.4E−03) | 0.09 (p = 1.6E−02) |
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 213 (p = 9.4E−06) | 0.00069 (p = 6.6E−01) | 8254.8 (p = 2.6E−07) | 0.12 (p = 4.6E−03) |
