Table 1 Patients baseline characteristics (n = 110 and sample characteristics (n = 164).

From: Analysis of expression of the PD-1/PD-L1 immune checkpoint system and its prognostic impact in gastroenteropancreatic neuroendocrine tumors

Gender

Number of patients (percentage)

Male

47 (42.7%)

Female

63 (57.3%)

Age, years

<55

46 (41.8%)

≥55

64 (58.2%)

Stage (ENETS)

I

32 (29.1%)

II

20 (18.2%)

III

19 (17.3%)

IV

36 (32.7%)

Unknown

3 (2.7%)

Disease Type

No residual disease

66 (60.0%)

Stable disease

17 (15.5%)

Progressive disease

22 (20.0%)

Unknown

5 (4.6%)

Primary site

Pancreatic NET

48 (43.6%)

Gastrointestinal NET

62 (56.4%)

Primary tumor size, cm

<3.0

69 (62.7%)

≥3.0

37 (33.7%)

Unknown

4 (3.6%)

Grading (WHO 2010 criteria)

G1

66 (60%)

G2

34 (30.9%)

G3

4 (3.6%)

Unknown

6 (5.5%)

Adjuvant therapy

Somatostatin analogues

36 (32.7%)

Interferon

8 (7.3%)

Cytotoxic chemotherapy

5 (4.6%)

Sunitinib

1 (0.9%)

Everolimus

4 (3.6%)

Sample characteristics (n = 164)

Primary Tumor tissue

104 (63.4%)

Metastatic Tumor Tissue

12 (7.3%)

Non-tumor adjacent tissues

48 (29.3%)

  1. Abbreviations: TNM: Tumor, lymph Node, Metastasis; ENETS: European Neuroendocrine Tumor Society; NET: Neuroendocrine Tumor; WHO: World Health Organization; G1: Grade 1; G2: Grade 2; G3: Grade 3.