Figure 3 | Scientific Reports

Figure 3

From: Targeted-pig trial on safety and immunogenicity of serum-derived extracellular vesicles enriched fractions obtained from Porcine Respiratory and Reproductive virus infections

Figure 3

Protein identification pipeline from PRRSV convalescent sera EV-enriched fractions. Liquid chromatography (nanoLCULTRA-EKSIGENT) followed by mass spectrometry (LC-MS/MS) of EV-enriched fractions identified viral peptides with a FDR < 1% and at least two peptides from the same protein. Two different algorithms were used to examine matching regions between our identified peptides (LC-MS/MS) and possible B-cell epitopes or antigenic regions within the protein14,15.

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