Figure 5
From: Human Herpesvirus 6A and 6B inhibit in vitro angiogenesis by induction of Human Leukocyte Antigen G
Modulation of human transcription factors by HHV-6 infection or U94 transfection/protein treatment. HUVECs were infected with HHV-6A, or HHV-6B, or HHV-7 (as a control Roseolovirus, since it lacks U94 gene), or transfected with a U94 coding plasmid (p-U94), or treated with the U94 recombinant protein (U94rec). After 12 hours total RNA was extracted and assayed by a specific microarray detecting transcriptional factor expression. Control cells were untreated. Results are expressed as mean values of fold regulation compared to control values in triplicate samples.
