Table 1 Demographic characteristics.

From: CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation

Variables

Total (n = 1,080)

≤7 METs (n = 131)

>7 METs (n = 949)

P value*

Age (years)

65 ± 11

71 ± 8

64 ± 11

<0.0001

  Age <65

509 (47.1)

23 (17.6)

486 (51.2)

<0.0001

  Age 65–74

391 (36.2)

64 (48.9)

327 (34.5)

0.001

  Age ≥75

180 (16.7)

44 (33.6)

136 (14.3)

<0.0001

Male

769 (71.2)

70 (53.4)

699 (73.7)

<0.0001

Body mass index (kg/m2)

24.9 ± 3.2

25.5 ± 3.7

24.8 ± 3.1

0.048

Duration of AF ( ≥ 3 months)

932 (86.3)

114 (87.0)

818 (86.2)

0.893

Type of AF

  Paroxysmal

817 (75.6)

89 (67.9)

728 (76.7)

0.028

  Persistent

234 (21.7)

40 (30.5)

194 (20.4)

0.009

  Permanent

29 (2.7)

2 (1.5)

27 (2.8)

0.566

Diabetes mellitus

263 (24.4)

48 (36.6)

215 (22.7)

<0.0001

Hypertension

747 (69.4)

114 (87.0)

633 (66.9)

<0.0001

Stroke/TIA

111 (10.3)

97 (10.2)

14 (10.7)

0.892

Peripheral artery disease

22 (22.0)

5 (3.8)

17 (1.8)

0.174

Dyslipidemia

437 (40.7)

54 (41.5)

383 (40.5)

0.826

Chronic kidney disease

100 (9.3)

20 (15.3)

80 (8.4)

0.011

Smoking

405 (37.5)

41 (31.3)

364 (38.4)

0.118

Medications

  ACEi or ARB

381 (35.3)

65 (49.6)

316 (33.3)

<0.0001

  Beta-blocker

529 (49.0)

72 (55.0)

457 (48.2)

0.144

  Calcium channel blocker

339 (31.4)

59 (45.0)

280 (29.5)

<0.0001

  Digoxin

35 (3.2)

7 (5.3)

28 (3.0)

0.181

  Antiarrhythmic drug

624 (57.8)

70 (53.4)

554 (58.4)

0.283

  1. *P value: ≤7 METs vs. >7 METs.
  2. Values are presented as the mean ± SD or n (%).
  3. Abbreviations: MET = metabolic equivalent; TIA = transient ischemic attack; AF = atrial fibrillation; ACEi = angiotensin converting enzyme inhibitor; ARB = angiotensin receptor blocker.