Table 3 Univariate and multivariate analysis for exercise intolerance.

From: CHA2DS2-VASc score predicts exercise intolerance in young and middle-aged male patients with asymptomatic atrial fibrillation

Variables

Univariate analysis

Multivariate analysis

OR

95% CI

P value

OR

95% CI

P value

CHA2DS2-VASc score*

1.60

1.41–1.80

<0.0001

1.54

1.31–1.81

<0.0001

BMI (kg/m2)

1.06

1.01–1.12

0.025

1.05

0.99–1.12

0.115

Smoking

0.73

0.50–1.08

0.119

1.34

0.83–2.16

0.229

Chronic kidney disease

1.96

1.15–3.32

0.013

0.97

0.50–1.89

0.924

Persistent AF**

1.69

1.13–2.53

0.011

1.25

0.74–2.13

0.407

Permanent AF**

0.61

0.14–2.59

0.499

0.79

0.09–6.76

0.832

QTc interval (ms)

1.01

1.00–1.02

0.001

1.01

1.00–1.02

0.026

LVEF (%)

1.01

0.98–1.04

0.542

1.01

0.97–1.05

0.659

E/E’

1.10

1.05–1.15

<0.0001

1.01

0.96–1.07

0.656

LAVI (ml/m2)

1.02

1.02–1.03

<0.0001

1.02

1.01–1.03

0.001

Resting DBP (mmHg)

0.97

0.96–0.99

0.003

0.98

0.96–1.00

0.054

Resting HR (bpm)

1.01

0.99–1.02

0.206

1.01

0.99–1.02

0.259

Use of beta-blocker

1.31

0.91–1.90

0.145

1.14

0.73–1.78

0.572

  1. *Excluding congestive heart failure component, **versus paroxysmal AF.
  2. Abbreviations: OR = odds ratio; CI = confidence interval; BMI = body mass index; AF = atrial fibrillation; LVEF = left ventricular ejection fraction; LAVI = left atrial volume index; DBP = diastolic blood pressure; HR = heart rate.
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