Figure 3

Socially acquired nicotine self-administration, fixed ratio 10. Rats were split into high vs low nicotine intake groups for each sex based on the median of nicotine infusion during the 10 fixed-ratio sessions. The high intake groups licked significantly more on the active spouts compared to the inactive spout (A), while the reverse was true for the low intake group (B). Error bars in these panels represent standard errors. The mean nicotine intake (log transformed) during the 10 fixed-ratio sessions is shown as a box plot (C), where the thick black line in the middle of the boxes represent the median, the height of the boxes represent the interquartile range (IQR), the top and bottom hinges represent the ±1.5 IQR, and the grey circles represent individual data points that are outliers. The total nicotine infusion during the 10 sessions for females and males (log transformed) are shown as histograms in (D).