Figure 4
From: Corynebacterium Cell Factory Design and Culture Process Optimization for Muconic Acid Biosynthesis
Time course profiles of cell growth, agitation speed, DO concentration, pH, DCW, glucose, organic acids and metabolite production by the STR011 strain in the 7-L fermenter. (A) The feeding medium was sequentially injected at cultivation time periods of 32, 44, 88, 95 and 162 h at a rate of 0.2268 mL/min, 0.3402 mL/min, 0.2268 mL/min, 0.2835 mL/min and 0.3402 mL/min. (B) The feeding medium was sequentially injected at cultivation time periods of 39, 52, 80, 85, 91.5, and 117 h at a rate of 0.2268 mL/min, 0.3402 mL/min, 0.2268 mL/min, 0.2835 mL/min, 0.3402 mL/min, 0.4536 mL/min. During the fed-batch cultivation, 230.2 g/L and 227 g/L of glucose was totally added, respectively.
