Table 4 List of annotated DEGs among common gene after three pathogens infection.

From: Gene expression profiles alteration after infection of virus, bacteria, and parasite in the Olive flounder (Paralichthys olivaceus)

Gene Expression Change (Control → Infection)

Gene Accession

Description

Fold change (log2) (Bacteria/control)

Fold change (log2) (Virus/control)

Fold change (log2) (Parasite/control)

Predicted gene symbol

UP

GENE19852.r1

Fibroblast growth factor 4 [Source:SWISS;Acc:P48804]

0.658

0.661

0.782

FGF4

Down

GENE00707.r1

Acidic mammalian chitinase [Source:SWISS;Acc:Q91XA9]

−0.540

−1.386

−1.367

Chia

GENE16184.r1

Rab GDP dissociation inhibitor beta [Source:SWISS;Acc:P50395]

−1.739

−1.399

−1.218

GDI2

GENE11810.r1

Neuronal acetylcholine receptor subunit alpha-7 [Source:SWISS;Acc:P22770]

−1.041

−1.566

−2.009

CHRNA7

GENE04169.r1

Histidine decarboxylase [Source:SWISS;Acc:P23738]

−1.177

−1.173

−1.266

Hdc

GENE11460

Semaphorin-3E [Source:SWISS;Acc:O42237]

−1.454

−2.466

−1.203

SEMA3E

GENE21840.r1

Cysteine-rich secretory protein LCCL domain-containing 1 [Source:SWISS;Acc:Q8CGD2]

−0.705

−1.769

−1.146

Crispld1

GENE23270.r1

Cx9C motif-containing protein 4 [Source:SWISS;Acc:P56277]

−1.562

−3.848

−2.557

CMC4*

GENE06025.r1

Protein phosphatase 1 regulatory subunit 3C-B [Source:SWISS;Acc:Q6P950]

−0.829

−1.627

−1.308

ppp1r3cb

GENE18715.r1

Collagen alpha-2(I) chain [Source:SWISS;Acc:O46392]

−3.069

−5.000

−2.317

COL1A2*

GENE18863

2-aminoethanethiol dioxygenase [Source:SWISS;Acc:Q6PDY2]

−1.029

−2.165

−1.399

Ado

GENE05041.r1

AP-1 complex subunit sigma-3 [Source:SWISS;Acc:Q7TN05]

−1.146

−1.544

−1.340

Ap1s3

GENE03465

Homeobox protein Nkx-3.1 [Source:SWISS;Acc:Q99801]

−1.078

−3.351

−1.063

NKX3-1

GENE24080.r1

Transmembrane protein 205 [Source:SWISS;Acc:A1L2F6]

−0.743

−2.695

−0.980

tmem205

GENE14826.r1

Ethanolamine-phosphate phospho−lyase [Source:SWISS;Acc:Q7SY54]

−1.289

−1.961

−1.274

etnppl

GENE01095.r1

Alcohol dehydrogenase 1 [Source:SWISS;Acc:P26325]

−0.750

−1.348

−0.906

ADH1_GADMC

GENE12085.r1

Pyridine nucleotide-disulfide oxidoreductase domain−containing protein 2 [Source:SWISS;Acc:Q68FT3]

−0.953

−1.658

−0.839

Pyroxd2

GENE22874.r1

Potassium voltage-gated channel subfamily KQT member 3 [Source:SWISS;Acc:Q8K3F6]

−0.616

−0.475

−0.785

Kcnq3

GENE06563

Protein Hook homolog 3 [Source:SWISS;Acc:Q6GQ73]

−1.723

−4.109

−1.638

hook3

GENE01318.r1

Mitochondrial peptide methionine sulfoxide reductase [Source:SWISS;Acc:P54149]

−0.693

−1.130

−0.953

MSRA

GENE02237.r1

Anterior gradient protein 3 homolog [Source:SWISS;Acc:Q8TD06]

−1.288

−3.663

−1.523

AGR3

GENE11050.r1

Viral T−cell receptor beta chain-like T17T-22 [Source:SWISS;Acc:P11364]

−1.211

−3.670

−1.053

V-TCR

GENE09774

Claudin-12 [Source:SWISS;Acc:Q5R9K1]

−0.685

−2.185

−0.839

CLDN12

GENE11823.r1

Proline-rich protein 5-like [Source:SWISS;Acc:A2AVJ5]

−0.924

−1.909

−0.949

Prr5l

GENE03568.r1

Urea transporter 2 [Source:SWISS;Acc:Q28614]

−2.107

−4.956

−2.405

SLC14A2*

GENE06547

Krueppel-like factor 5 [Source:SWISS;Acc:Q9Z0Z7]

−1.264

−2.379

−1.251

Klf5

GENE09838.r1

Integrin alpha-10 [Source:SWISS;Acc:O75578]

−1.017

−2.154

−1.004

ITGA10

GENE21626.r1

Hydroxycarboxylic acid receptor 2 [Source:SWISS;Acc:Q8TDS4]

−1.033

−2.299

−1.053

HCAR2

GENE01511.r1

Ectonucleoside triphosphate diphosphohydrolase 5 [Source:SWISS;Acc:O75356]

−1.063

−1.592

−0.818

ENTPD5

GENE15828.r1

Matrix metalloproteinase-20 [Source:SWISS;Acc:O18767]

−1.145

−2.128

−0.738

MMP20

GENE06887.r1

Osteocalcin [Source:SWISS;Acc:P02823]

−2.740

−3.546

−1.659

bglap*

GENE01596.r1

GTP cyclohydrolase 1 feedback regulatory protein [Source:SWISS;Acc:Q6PBT6]

−1.253

−2.255

−0.904

gchfr

GENE16851.r1

Aminopeptidase N {ECO:0000312|EMBL:ACZ95799.1} [Source:SWISS;Acc:O57579]

−1.504

−3.185

−2.428

ANPEP*

XLOC_002910

Trypsin-1 [Source:SWISS;Acc:P35031]

−1.401

−1.350

−2.147

TRY1_SALSA

XLOC_021180

Collagen alpha-1(I) chain [Source:SWISS;Acc:P02457]

−2.092

−5.204

−2.025

COL1A1*

XLOC_036089

AT-hook-containing transcription factor [Source:SWISS;Acc:Q80VW7]

−1.577

−2.290

−1.507

Akna

XLOC_029355

Collagen alpha-3(VI) chain [Source:SWISS;Acc:P15989]

−1.301

−3.553

−0.819

COL6A3

  1. *Six genes with asterisk are representive genes which have fold change (log2) of <−2.0 in at least two pathogen groups. p < 0.05.