Figure 1 | Scientific Reports

Figure 1

From: Quantifying site-specific chromatin mechanics and DNA damage response

Figure 1

Bulk chromatin motion measurements are independent of bound probe. Nuclei in both cases are stained with Hoechst 33342 (a) U2OS cell transfected with GFP-Fibrillarin showing localization of Fibrillarin within nucleoli. (b) U2OS cell transfected with RFP-TRF1 showing TRF1 localization at telomeres. (c) MSDs of RFP-TRF1 (n = 17), in red, and GFP-Fibrillarin (n = 13), in green, tracked in untreated control U2OS cells. Lines lie atop each other indicating that measurements of MSDs taken from different probes yield equivalent results. Error bars are SEM.

Back to article page