Figure 4
B cell profiles at different times for model A. (A) Non-adjuvanted case; (B) MF59; (C) AS03; (D) Diluvac. Each column represents a snapshot of the B cell distribution in shape space at the time stated above the top panel. By construction, differences between the adjuvanted and non-adjuvanted formulations are not clearly discernible here, due to the fact that the immunogenicity-weighted affinity has little effect on B cell dynamics, and the unweighted affinity takes a more important role.
