Figure 5

Antibody profiles at different times for model A. (A) Non-adjuvanted case; (B) MF59; (C) AS03; (D) Diluvac. Each column represents a snapshot of the Ab distribution in shape space at the time stated above the top panel. In contrast to Fig. 4, here the effects of the adjuvants are clearly visible: we observe the shifts in the scale of the Ab response, much larger in the case of squalene-containing adjuvants, as well as a leveling of the relative heights of the left- and right-most portions of Ab distribution with respect to the non-adjuvanted case, corresponding to the NA- and HA-specific responses, respectively.