Figure 2

Levels of inflammatory cytokines and IFNs in IAE model mice. Gene expressions of Tnfa (a), Il6 (b), Il1b (c), Ifna4 (d), Ifnb1 (e), and Ifng (f) from whole brains at 8 h and 24 h post LPS administration were analysed by quantitative PCR. Data are shown as the mean ± SEM (8 h control, n = 5; Flu, n = 3; LPS, n = 5; Flu + LPS, n = 5; 24 h control, n = 5; Flu, n = 5; LPS, n = 3; Flu + LPS, n = 6) and are from a representative experiment of two or three independent experiments. *p < 0.05; **p < 0.01; ***p < 0.001.