Table 1 Association between rs3782499 and DDH in the two-stage population.

From: Genetic variant of WIF1 gene is functionally associated with developmental dysplasia of the hip in Han Chinese population

 

Genotype

Allele Frequency

P value

AA

AG

GG

No.

A

G

A vs G/OR(95%)a

AA vs others/OR(95%)

GG vs others/OR(95%)

Stage 1

Case

280

100

6

386

0.86

0.15

0.002/0.68(0.53–0.87)

0.005/1.50(1.13–1.99)

0.045/0.40(0.16–1.01)

Control

356

181

21

558

0.80

0.20

Stage 2

Case

145

52

3

200

0.86

0.15

0.008/0.65(0.47–0.90)

0.018/1.55(1.08–2.24)

0.063/0.33(0.10–1.12)

Control

270

140

19

429

0.79

0.21

Total

Case

425

152

9

586

0.85

0.15

4.37*10 −5 /0.67(0.55–0.81)

0.005/1.52(1.22–1.90)

0.005/0.37(0.18–0.77)

Control

626

321

40

987

0.80

0.20

  1. aOR, Odds Ratio; OR(95% confidence interval(CI)) was shown as effect allele vs reference allele. P values were derived from Bilateral chi square tests to determine the significance of differences.
Back to article page