Table 1 Tentative assignments of the vibrational of the human breast and brain tissue from the Raman spectra.

582

Glycans

606

Undefined

720

Phospholipid (choline)^1,44,45

751

Nucleic acids, Trp

825

Lactic acid

840

Tyr, proline, glycogen⁴⁶

858

Glycans, N-acetyloglucosamine, O-S-O (GAG), glycogen

883

Tyr, Lipids/Carbohydrates/Collagen⁴⁷

C-C-N⁺, C-O-C ring, C-C

895

Glycans

917

C-C stretching of proline, glucose, lactic acid⁴⁶

925

Glycans, glycogen, N-acetyloglucosamine

958

Hydroxyproline/Collagen backbone^41,48

CH=CH bending

997

C-C symmetric stretching, glucose-I-phosphate, symmetric breathing mode of phenylalanine⁴⁶

1004 (R)

Phenylalanine^42,49,50,51 symmetric ring breathing of protein⁵¹

1064

Lipids/Collagen^41,47 C-C str.

1091

Phospholipids, O-P-O symmetric stretching⁴¹, P=O symmetric vibration from nucleic acids/cell membrane phospholipids

1120

GAG, S=O stretching

1080–1158

Proteins (C-C/C-N str.)^47,52,53, P=O symmetric vibration from nucleic acids and phospholipids

L-Tryptophan⁵¹

1189 (R)

C-C₆H₅ Phe, Trp⁴⁷

1238

Phospholipid, O-P-O antisymmetric stretching⁵⁴ Amide III β−sheet⁴⁶

1242

GAG S=O stretching

1248

Nucleic acids (Try, Ala)/Proteins (Amide III β sheet or random coil), Lipid, phospholipid =C-H bending^41,47

1267

Fatty acids, =C-H bend^41,47

1276

Amide III⁴⁶ α helix, P=O asymmetric stretching due to nucleic acids

1281

GAG

1304(R)

Lipids, phospholipids⁴¹ C-H₂ twist, collagen, protein amide III⁴⁶, DNA⁴⁶

1327

N-acetyloglucosamine

1339/1370

Trp, C_a-H def

1378

N-acetyloglucosamine

1437–1444

1453

Fatty acids, triglycerides, CH₂ or CH₃ deformations⁵³

Proteins^3,51 C-H wag, CH₂ or CH₃ def. Phospholipids, CH₂ scissoring⁵⁵

1484

Glycans

1558

Amide II, proteins^41,48, amide II β−sheet⁵²

1584

Amide II⁴⁵, aromatic amino acids within proteins⁵³, nucleic acids^41,47

1651

(C=C) stretching, unsaturated fatty acids, triglycerides

1658

(C=C) stretching⁵³, Amide I α helix

1667–1680

Proteins, Amide I β−sheet, cholesterol esters⁴⁶

1667–1680

Proteins Amide I turn⁴⁴/Unsaturated fatty acids^47,51, (C=O) stretching, (C-H) def./(C=C) str.^47,51, collagen, elastin⁴¹

1745

1731

(C=O) stretching, triglycerides

(C=O) stretching, glycans, glycogen

2845/2854

Fatty acids, triglycerides, C-H₂ symmetric stretching

2888

Lipids⁵¹, C-H₂ antisymmetric stretching

2905

proteins/lipids C-H₂ antisymmetric stretching^56,57,58,59 CH₃ symmetric stretching^41,58,60 C-H₂ antisymmetric stretching, Lysine²³, glycogen

2931/2940

Proteins/Lipids, CH₃ symmetric stretching^41,51 CH₃ symmetric stretching Acetylated lysine²³ Proteoglycans, Heparan sulfate, Chondroitin sulfate

2963

Methylated lysine²³

3009

Lipids^41,51=C-H stretching

3067

Nucleic acids/Proteins⁵¹ C-H aromatic